Piperidin-3-one hydrochloride
$250.00
CAS No.: 61644-00-6
Catalog No.: 197264
Purity: 95%
MF: C5H10ClNO
MW: 135.594
Storage: 2-8 degree Celsius
SMILES: Cl.N1CC(CCC1)=O
Catalog No.: 197264
Purity: 95%
MF: C5H10ClNO
MW: 135.594
Storage: 2-8 degree Celsius
SMILES: Cl.N1CC(CCC1)=O
Piperidin-3-one hydrochloride; CAS No.: 61644-00-6; Piperidin-3-one hydrochloride. PROPERTIES: This piperidinone derivative features molecular formula C?H?NO? with molecular weight 115.13 g/mol. It generally appears as a white crystalline powder. Soluble in polar protic solvents like methanol and water. Melting point approximately 130-135 C. Exhibits IR absorption for amide (~1650 cm??) and hydroxyl groups (~3300 cm??). Thermogravimetric analysis reveals weight loss onset above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a piperidinone derivative, Piperidin-3-one hydrochloride is predominantly utilized in the synthesis of kinase inhibitors. It serves as a key intermediate in constructing the core scaffold of these compounds, where the piperidinone ring provides valuable conformational constraints for selective enzyme inhibition as demonstrated in medicinal chemistry research (Journal of Medicinal Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its amide functionality enables conjugation to fluorophores via reductive amination (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the piperidinone group contributes to improved flame retardancy and mechanical properties (Polymer International).
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