PEG9-Bis-t-butyl ester
$250.00
CAS No.: 2225903-62-6
Catalog No.: 199646
Purity: 95%
MF: C30H58O13
MW: 626.781
Storage: 2-8 degree Celsius
SMILES: C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)OC(C)(C)C)(=O)OC(C)(C)C
Catalog No.: 199646
Purity: 95%
MF: C30H58O13
MW: 626.781
Storage: 2-8 degree Celsius
SMILES: C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)OC(C)(C)C)(=O)OC(C)(C)C
CAS No.: 2225903-62-6; PEG9-Bis-t-butyl ester. PROPERTIES: PEG9-Bis-t-butyl ester is a colorless to pale yellow viscous liquid with a molecular weight of approximately 714.8 g/mol. Its chemical formula is C27H50O11. The compound is soluble in common organic solvents such as chloroform and methanol. It requires storage at 2-8 C in airtight containers to prevent hydrolysis. The substance is sensitive to moisture and should be handled under dry conditions. Safety considerations include using PPE to prevent skin contact and avoiding inhalation of vapors. The compound may cause mild skin irritation and is not classified as harmful. APPLICATIONS: PEG9-Bis-t-butyl ester is a PEGylation reagent with dual t-butyl ester groups. It is utilized in modifying proteins and peptides to enhance their solubility and stability. The PEG chain provides steric protection against enzymatic degradation. Applications include the development of long-acting therapeutic proteins and peptide drugs. The compound has been employed in creating site-specific PEGylated biotherapeutics with improved pharmacokinetic profiles. Additionally, it serves as a building block in the synthesis of advanced drug delivery vehicles incorporating PEG moieties. These applications are documented in pharmaceutical chemistry textbooks and specialized research publications on biopharmaceutical development.
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