CAS NO.: 145218-19-5; 5-Bromo-2-(bromomethyl)pyridine. PROPERTIES: 5-Bromo-2-(bromomethyl)pyridine is a solid with two bromine substituents on the pyridine ring. It has limited solubility in water and is more soluble in organic solvents like chloroform or ethyl acetate. This compound is sensitive to moisture and air, so it should be stored in a dry, inert atmosphere, preferably in a refrigerator. It is highly reactive due to the presence of the bromine atoms, which can easily participate in nucleophilic substitution reactions. When handling, protective equipment, including gloves and goggles, is essential, as it can cause severe skin and eye damage. APPLICATIONS: In organic synthesis, 5-bromo-2-(bromomethyl)pyridine is a versatile building block. The bromine atoms can be replaced by various nucleophiles, allowing for the construction of complex pyridine-based molecules. It is used in the synthesis of pharmaceuticals, agrochemicals, and materials with pyridine moieties, which often exhibit important biological and physical properties. Its application in synthetic chemistry is based on the reactivity of bromine-substituted pyridines and the requirements for creating functionalized pyridine compounds, as described in organic synthesis textbooks and research articles.