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N-methyl-1-(pyrimidin-2-yl)methanamine; CAS No.: 1083246-53-0; N-methyl-1-(pyrimidin-2-yl)methanamine. PROPERTIES: N-methyl-1-(pyrimidin-2-yl)methanamine has molecular formula C7H11N3 with molecular weight approximately 133.18 g/mol. It typically forms colorless oils with a mild amine odor. The compound demonstrates moderate solubility in polar organic solvents and limited water solubility. Proper storage involves keeping in a tightly sealed container at room temperature away from heat and direct sunlight. Safety considerations include using adequate ventilation during handling to prevent inhalation of vapors, which may cause respiratory irritation. The amine groups may react with electrophilic substances, so compatibility should be verified. In case of eye contact, immediate flushing with water for at least 15 minutes is advised. APPLICATIONS: N-methyl-1-(pyrimidin-2-yl)methanamine serves as a specialized intermediate in pharmaceutical synthesis. Its methyl substitution improves metabolic stability in biological systems. In medicinal chemistry, it has been employed in developing novel antidepressant agents targeting monoamine transporters, as documented in psychopharmacology-focused pharmaceutical research journals. The pyrimidinylmethanamine structure enables receptor binding interactions critical for biological activity. Additionally, this compound acts as a building block for veterinary pharmaceuticals, with applications reported in veterinary medicinal chemistry literature focusing on anxiolytic agents.