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N-methyl-1-(pyrimidin-2-yl)methanamine hydrochloride; CAS No.: 1956365-37-9; N-methyl-1-(pyrimidin-2-yl)methanamine hydrochloride. PROPERTIES: This compound appears as a white crystalline powder with molecular formula C6H10N3 {HCl and a molecular weight of 158.61 g/mol. It demonstrates a melting point in the range of 188-192 C and shows good solubility in water and common polar solvents like methanol. The substance is hygroscopic and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at room temperature with protection from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as N-methyl-1-(pyrimidin-2-yl)methanamine hydrochloride may cause skin and eye irritation. The amine group requires careful handling in strongly acidic environments. APPLICATIONS: In the pharmaceutical industry, N-methyl-1-(pyrimidin-2-yl)methanamine hydrochloride serves as an intermediate for synthesizing cardiovascular agents, as described in medicinal chemistry literature focusing on beta-blockers. Its amine substituent enables formation of bioactive amides through amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with insecticidal activities through formation of urea derivatives. Academic research has explored its potential in bioconjugation reactions for creating targeted therapeutic agents, as reported in biochemical journals. The pyrimidine ring system also facilitates coordination with metal ions, making it valuable for creating coordination polymers in materials science applications, as evidenced by structural chemistry publications.