N-(3,5-difluorophenyl)acetamide; CAS No.: 404-01-3; N-(3,5-difluorophenyl)acetamide. PROPERTIES: N-(3,5-difluorophenyl)acetamide is a crystalline solid. Its molecular formula is C9H8F2NO, and the molecular weight is approximately 186.17 g/mol. The compound has a melting point of approximately 85-87 C. It is slightly soluble in water but dissolves well in organic solvents such as methanol and dimethylformamide. For proper storage, it should be kept in a sealed container at room temperature, away from heat and direct sunlight. As a compound containing an amide group and difluorinated phenyl group, it may exhibit certain reactivity and stability. When handling it, protective gloves and eye protection should be worn. In case of accidental contact with skin or eyes, immediate rinsing with water is necessary. APPLICATIONS: In organic synthesis, N-(3,5-difluorophenyl)acetamide serves as a versatile intermediate. The amide group can undergo various reactions such as hydrolysis, acylation, and amidation. The difluorinated phenyl group influences the electronic properties of the molecule. In the pharmaceutical industry, derivatives of this compound can be explored as potential drug candidates. For example, in the development of certain anti-inflammatory drugs, the structure of N-(3,5-difluorophenyl)acetamide can be modified to enhance the drug's efficacy and reduce side effects (as reported in medicinal chemistry journals). Additionally, in the field of chemical research, it can be used as a starting material for the synthesis of novel organic compounds with potential applications in catalysis and sensing (as noted in organic chemistry research papers).