N-(2-chloro-4-fluoro-6-methylphenyl)acetamide
$375.00
CAS No.: 1710696-26-6
Catalog No.: 193105
Purity: 95%
MF: C9H9ClFNO
MW: 201.628
Storage: 2-8 degree Celsius
SMILES: ClC1=C(C(=CC(=C1)F)C)NC(C)=O
Catalog No.: 193105
Purity: 95%
MF: C9H9ClFNO
MW: 201.628
Storage: 2-8 degree Celsius
SMILES: ClC1=C(C(=CC(=C1)F)C)NC(C)=O
N-(2-chloro-4-fluoro-6-methylphenyl)acetamide; CAS No.: 1710696-26-6; N-(2-chloro-4-fluoro-6-methylphenyl)acetamide. PROPERTIES: This compound appears as a white crystalline powder with molecular formula C9H9ClFNO and a molecular weight of 208.63 g/mol. It demonstrates a melting point in the range of 112-116 C and shows moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as N-(2-chloro-4-fluoro-6-methylphenyl)acetamide may cause skin irritation. The acetamide group requires careful handling in strongly basic environments. APPLICATIONS: In medicinal chemistry, N-(2-chloro-4-fluoro-6-methylphenyl)acetamide serves as a key intermediate for synthesizing anticancer agents, as documented in pharmaceutical research focusing on kinase inhibitors. Its chloro and fluoro substituents enable participation in cross-coupling reactions for constructing biaryl systems. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through nucleophilic aromatic substitution reactions. Academic studies have explored its potential in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The phenylacetamide structure also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
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