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N-(2-bromo-5-methylphenyl)acetamide

$150.00
CAS No.: 126759-48-6
Catalog No.: 193912
Purity: 95%
MF: C9H10BrNO
MW: 228.089
Storage: 2-8 degree Celsius
SMILES: BrC1=C(C=C(C=C1)C)NC(C)=O
For R&D use only. Not for human or animal use.
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N-(2-bromo-5-methylphenyl)acetamide; CAS No.: 126759-48-6;N-(2-bromo-5-methylphenyl)acetamide. PROPERTIES: N-(2-bromo-5-methylphenyl)acetamide is a brominated and methylated aromatic amide with molecular formula C9H9BrNO. It typically exists as a colorless to pale yellow crystalline solid with a melting point of approximately 65-70 C. The compound has limited water solubility but dissolves in organic solvents like ethanol or acetone. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong oxidizing agents, releasing toxic bromine vapors. Proper storage involves keeping it in tightly sealed containers below 25 C, protected from light and moisture. APPLICATIONS: In organic synthesis, this compound serves as a versatile intermediate for creating complex aromatic molecules. The bromo substituent provides a site for cross-coupling reactions to form biaryl structures, while the acetamide group offers additional functionality for further elaboration (The Journal of Organic Chemistry). In pharmaceutical development, N-(2-bromo-5-methylphenyl)acetamide contributes to the synthesis of antimicrobial agents where the halogenated aromatic scaffold enhances binding to microbial targets (Antimicrobial Agents and Chemotherapy). The compound also finds application in materials science as a building block for organic electronics, where its electron-deficient aromatic core modulates the electronic properties of derived materials (Advanced Materials).

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