methyl 6-amino-2-methoxynicotinate
$490.00
CAS No.: 149539-81-1
Catalog No.: 193098
Purity: 95%
MF: C8H10N2O3
MW: 182.179
Storage: 2-8 degree Celsius
SMILES: NC1=NC(=C(C(=O)OC)C=C1)OC
Catalog No.: 193098
Purity: 95%
MF: C8H10N2O3
MW: 182.179
Storage: 2-8 degree Celsius
SMILES: NC1=NC(=C(C(=O)OC)C=C1)OC
methyl 6-amino-2-methoxynicotinate; CAS No.: 149539-81-1; methyl 6-amino-2-methoxynicotinate. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C9H11N3O2 and a molecular weight of 193.20 g/mol. It exhibits a melting point in the range of 142-146 C and demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as methyl 6-amino-2-methoxynicotinate may cause skin irritation. The amino group requires careful handling in strongly acidic environments. APPLICATIONS: In medicinal chemistry, methyl 6-amino-2-methoxynicotinate serves as a key intermediate for synthesizing antiviral agents, as documented in pharmaceutical research focusing on nucleoside analogs. Its amino substituent enables formation of bioactive amides through amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its potential in bioconjugation reactions for creating targeted therapeutic agents, as reported in biochemical journals. The nicotinate ester group also facilitates improved solubility in organic media, making it valuable for formulation purposes in pharmaceutical and agrochemical applications, as evidenced by studies in medicinal and agricultural chemistry literature.
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