methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pentanoate
$250.00
CAS No.: 1985620-97-0
Catalog No.: HKP0249
Purity: 95%
MF: C12H23BO4
MW: 242.124
Storage: 2-8 degree Celsius
SMILES: COC(CCCCB1OC(C(O1)(C)C)(C)C)=O
Catalog No.: HKP0249
Purity: 95%
MF: C12H23BO4
MW: 242.124
Storage: 2-8 degree Celsius
SMILES: COC(CCCCB1OC(C(O1)(C)C)(C)C)=O
CAS NO.: 1985620-97-0;methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pentanoate. PROPERTIES: This boronate ester derivative presents as a colorless liquid with a molecular weight of approximately 259.3 g/mol. The methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pentanoate combines a boronate ester group with a pentanoate ester, exhibiting limited aqueous solubility but good dissolution in polar aprotic solvents like THF and DMF. Stability characterization reveals vulnerability to hydrolysis and sensitivity to air moisture, necessitating storage at 2-8 degree Celsius in sealed glass containers under nitrogen. Handlers should use powder hoods with HEPA filtration and wear cut-resistant gloves during handling. Skin contact may cause mild irritation requiring thorough washing. Inhalation may induce respiratory alkalosis; treatment includes humidified oxygen administration. Eye exposure requires extended rinsing and possible corticosteroid application. Waste should be hydrolyzed with dilute acid prior to disposal. APPLICATIONS: The methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pentanoate serves as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals (excluding agricultural applications). Its boronate ester group provides a valuable handle for Suzuki-Miyaura cross-coupling reactions. Research teams utilize this compound as a starting material for creating kinase inhibitors and nucleoside analogs. The ester group undergoes hydrolysis to carboxylic acids or reduction to alcohols for further functionalization. Its unique substitution pattern makes it valuable in the development of fluorescent probes and bioimaging agents.
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