methyl 2-amino-4-bromobenzoate
$400.00
CAS No.: 135484-83-2
Catalog No.: 196573
Purity: 95%
MF: C8H8BrNO2
MW: 230.061
Storage: 2-8 degree Celsius
SMILES: NC1=C(C(=O)OC)C=CC(=C1)Br
Catalog No.: 196573
Purity: 95%
MF: C8H8BrNO2
MW: 230.061
Storage: 2-8 degree Celsius
SMILES: NC1=C(C(=O)OC)C=CC(=C1)Br
methyl 2-amino-4-bromobenzoate; CAS No.: 135484-83-2; methyl 2-amino-4-bromobenzoate. PROPERTIES: This brominated amino ester is a white crystalline powder with molecular formula C9H8BrNO2. It has molecular weight of 254.07 g/mol and melting point around 65-70 C. The compound is moderately soluble in hot ethanol and methylene chloride but has limited water solubility. Recommended storage is in tightly sealed containers at 2-8 C to prevent moisture-induced hydrolysis of the ester group. Being a brominated compound, it may release toxic bromine vapors upon heating; proper ventilation is essential. APPLICATIONS: In pharmaceutical synthesis, this compound serves as intermediate for producing antimalarial agents. The amino group participates in heterocyclic ring formation while the bromine provides site for bioisosteric replacement during lead optimization (Journal of Medicinal Chemistry). In materials science, it acts as building block for producing liquid crystalline materials where the bromine substituent influences mesophase formation and transition temperatures (Liquid Crystals). The ester group enables further functionalization through hydrolysis or transesterification reactions. Additionally, it functions as starting material for producing fluorescent probes where the amino group is modified with fluorophores through acylation reactions (Analytical Chemistry). These applications exploit its combination of amino, bromo, and ester functionalities for constructing diverse pharmaceuticals and functional materials.
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