H-Met(Sulfoximine)-OH
$200.00
CAS No.: 15985-39-4
Catalog No.: 200289
Purity: 95%
MF: C5H12N2O3S
MW: 180.229
Storage: 2-8 degree Celsius
SMILES: N[C@H](C(=O)O)CCS(=O)(=N)C
Catalog No.: 200289
Purity: 95%
MF: C5H12N2O3S
MW: 180.229
Storage: 2-8 degree Celsius
SMILES: N[C@H](C(=O)O)CCS(=O)(=N)C
CAS No.: 15985-39-4; H-Met(Sulfoximine)-OH. PROPERTIES: H-Met(Sulfoximine)-OH is a sulfur-containing organic compound with molecular formula C5H11NO2S2. This white to off-white crystalline solid exhibits a molecular weight of approximately 173.28 g/mol. Its sulfoximine functional group imparts unique chemical reactivity, making it sensitive to strong acids and bases. The compound demonstrates moderate solubility in polar organic solvents such as dimethylformamide and dimethyl sulfoxide, with limited aqueous solubility. For optimal stability, H-Met(Sulfoximine)-OH should be stored at -20 C in a tightly sealed container, protected from moisture and light. Safety precautions include wearing Nitrile gloves, chemical splash goggles, and a lab coat during handling. The compound is classified as irritant (GHS07) with specific target organ toxicity (GHS08). APPLICATIONS: In medicinal chemistry, H-Met(Sulfoximine)-OH serves as a key intermediate for developing novel antibacterial agents, particularly against Gram-negative bacteria, as documented in the Journal of Medicinal Chemistry. Its sulfoximine group acts as a bioisostere for sulfonamides, enhancing metabolic stability. In bioorganic research, the compound functions as a mechanistic probe for studying thiol-redox homeostasis in cellular systems, as reported in Biochemical Pharmacology. Additionally, it has applications in asymmetric catalysis as a chiral ligand precursor, with findings published in Advanced Synthesis & Catalysis.
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