JMJD6 inhibitor WL12

JMJD6 inhibitor WL12

Galangin

$300.00
CAS No.: 548-83-4
Catalog No.: 198710
Purity: 95%
MF: C15H10O5
MW: 270.24
Storage: 2-8 degree Celsius
SMILES: OC1=C(OC2=CC(=CC(=C2C1=O)O)O)C1=CC=CC=C1
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CAS No.: 548-83-4; Galangin. PROPERTIES: Galangin is a flavonol with molecular formula C15H10O5 and molecular weight 282 g/mol. It appears as fine, pale yellow needles with melting point 267-270 C. Practically insoluble in water (<0.1 mg/mL) but dissolves in ethanol (1:100) and DMSO (1:20). Storage requires desiccator with silica gel at 4 C to prevent sublimation and oxidation. Safety precautions include avoiding dust inhalation and using laminar flow when handling due to its potential photosensitivity. In case of eye contact, rinse with water for 15 minutes and consult ophthalmologist. APPLICATIONS: Galangin demonstrates remarkable antioxidant capacity, scavenging DPPH radicals with IC50 of 12.5 M, making it valuable in cosmetic formulations for anti-aging products (as reported in International Journal of Cosmetic Science, 2021). In neuroscience research, Galangin inhibits acetylcholinesterase with Ki value of 0.43 M, showing promise for Alzheimer's disease treatment (documented in Journal of Natural Products, 2020). Its antimicrobial properties against MRSA (minimum inhibitory concentration 32 g/mL) position it as a lead compound for developing novel antimicrobials (described in Antimicrobial Agents and Chemotherapy, 2019). Additionally, Galangin modulates NF- B pathway, offering applications in inflammatory disease models, with preclinical data supporting its use in colitis and arthritis research.

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