Fmoc-L-Glu(2-phenylisopropyloxy)-OH
$350.00
CAS No.: 200616-39-3
Catalog No.: 200248
Purity: 95%
MF: C29H29NO6
MW: 487.552
Storage: 2-8 degree Celsius
SMILES: C1=CC=CC=2C3=CC=CC=C3C(C12)COC(=O)N[C@H](C(=O)O)CCC(OC(C)(C)C1=CC=CC=C1)=O
Catalog No.: 200248
Purity: 95%
MF: C29H29NO6
MW: 487.552
Storage: 2-8 degree Celsius
SMILES: C1=CC=CC=2C3=CC=CC=C3C(C12)COC(=O)N[C@H](C(=O)O)CCC(OC(C)(C)C1=CC=CC=C1)=O
CAS No.: 200616-39-3; Fmoc-L-Glu(2-phenylisopropyloxy)-OH. PROPERTIES: Fmoc-L-Glu(2-phenylisopropyloxy)-OH is a white to off-white solid with a molecular weight of approximately 433.5 g/mol. Its chemical formula is C23H25NO6. The compound is moderately soluble in common organic solvents such as dichloromethane and tetrahydrofuran. It requires storage at 2-8 C in airtight containers to prevent hydrolysis. The substance is sensitive to moisture and should be handled under dry conditions. Safety precautions include using PPE to prevent skin absorption and avoiding inhalation. The compound may cause skin irritation and serious eye damage. APPLICATIONS: Fmoc-L-Glu(2-phenylisopropyloxy)-OH is a protected L-glutamic acid derivative utilized in peptide synthesis. It incorporates a phenylisopropyl oxycarbonyl protecting group at the -amino group of glutamic acid. Applications include the synthesis of bioactive peptides with modified side chains for enhanced stability and activity. The compound has been employed in creating customized peptide sequences for vaccine development and in the preparation of peptide-based pharmaceutical intermediates. Additionally, it serves as a building block in the development of glutamate prodrugs with improved pharmacokinetic properties. These applications are documented in peptide synthesis textbooks and specialized research publications on medicinal chemistry.
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