ethyl 4-(2,2,2-trifluoroacetyl)benzoate
$300.00
CAS No.: 898787-14-9
Catalog No.: WLZ1563
Purity: 95%
MF: C11H9F3O3
MW: 246.184
Storage: 2-8 degree Celsius
SMILES: FC(C(=O)C1=CC=C(C(=O)OCC)C=C1)(F)F
Catalog No.: WLZ1563
Purity: 95%
MF: C11H9F3O3
MW: 246.184
Storage: 2-8 degree Celsius
SMILES: FC(C(=O)C1=CC=C(C(=O)OCC)C=C1)(F)F
CAS NO.: 898787-14-9; ethyl 4-(2,2,2-trifluoroacetyl)benzoate. PROPERTIES: This ester features a trifluoroacetyl group attached to a benzene ring connected to an ethyl ester, creating a molecule with potential applications in organic synthesis and pharmaceutical research. The ethyl 4-(2,2,2-trifluoroacetyl)benzoate typically appears as a colorless to pale yellow liquid with moderate solubility in common organic solvents. Its molecular structure includes an electrophilic trifluoroacetyl group that renders the molecule reactive toward nucleophilic substitution reactions. For optimal stability and to prevent premature reactions, this compound should be stored at 2-8 degree Celsius in an amber glass bottle under an inert atmosphere. When handling, appropriate safety measures including nitrile gloves and safety goggles are recommended. This compound is sensitive to moisture and may hydrolyze in aqueous environments. In case of skin contact, wash thoroughly with soap and water; if eye contact occurs, rinse immediately and seek medical advice. APPLICATIONS: The ethyl 4-(2,2,2-trifluoroacetyl)benzoate serves as a valuable building block in organic synthesis, particularly for creating fluoroacyl-containing bioactive molecules. The trifluoroacetyl group provides a handle for further reactions such as nucleophilic acyl substitutions. In medicinal chemistry, this compound functions as an intermediate for developing pharmaceuticals targeting enzyme inhibitors and receptor modulators. The fluorinated acetyl group contributes to target binding affinity and selectivity. Additionally, the molecule finds utility in materials science as a monomer for creating polymers with specific electronic and optical properties. Researchers utilizing this compound can benefit from its functional group versatility, enabling the development of diverse molecular architectures for applications ranging from drug discovery to advanced materials.
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