ethyl 2-nitro-4-(trifluoromethyl)phenylacetate
$300.00
CAS No.: 1357626-53-9
Catalog No.: 194106
Purity: 95%
MF: C11H10F3NO4
MW: 277.198
Storage: 2-8 degree Celsius
SMILES: [N+](=O)([O-])C1=C(C=CC(=C1)C(F)(F)F)CC(=O)OCC
Catalog No.: 194106
Purity: 95%
MF: C11H10F3NO4
MW: 277.198
Storage: 2-8 degree Celsius
SMILES: [N+](=O)([O-])C1=C(C=CC(=C1)C(F)(F)F)CC(=O)OCC
ethyl 2-nitro-4-(trifluoromethyl)phenylacetate; CAS No.: 1357626-53-9; ethyl 2-nitro-4-(trifluoromethyl)phenylacetate. PROPERTIES: ethyl 2-nitro-4-(trifluoromethyl)phenylacetate is a crystalline solid. Its molecular formula is C12H11F3NO5, and the molecular weight is approximately 308.22 g/mol. The compound has a melting point of approximately 75-77 C. It is moderately soluble in common organic solvents such as acetone and ethyl acetate, but is poorly soluble in water. For stable storage, it should be kept in a tightly sealed container at room temperature, away from heat and direct sunlight. As a nitro compound containing trifluoromethyl and ester groups, it may exhibit certain oxidizing properties and reactivity. When handling it, protective gloves and eye protection should be worn. In case of accidental contact with skin or eyes, immediate rinsing with water is necessary. APPLICATIONS: In organic synthesis, ethyl 2-nitro-4-(trifluoromethyl)phenylacetate serves as a versatile intermediate. The nitro group can be reduced to an amine group, the ester group can be hydrolyzed to a carboxylic acid, and the trifluoromethyl group provides unique electronic effects. In the pharmaceutical industry, derivatives of this compound can be explored as potential drug candidates. For example, in the development of certain antimicrobial agents, the unique substituents of ethyl 2-nitro-4-(trifluoromethyl)phenylacetate can be utilized to design drugs with enhanced antimicrobial activity and selectivity (as described in medicinal chemistry research articles). Additionally, in the field of chemical research, it can be used as a starting material for the synthesis of novel organic compounds with potential applications in materials science and catalysis (as noted in organic chemistry research papers).
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