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ethyl 2-bromobenzo[d]thiazole-6-carboxylate
$350.00
CAS No.: 99073-88-8
Catalog No.: 196163
Purity: 95%
MF: C10H8BrNO2S
MW: 286.15
Storage: 2-8 degree Celsius
SMILES: BrC=1SC2=C(N1)C=CC(=C2)C(=O)OCC
Catalog No.: 196163
Purity: 95%
MF: C10H8BrNO2S
MW: 286.15
Storage: 2-8 degree Celsius
SMILES: BrC=1SC2=C(N1)C=CC(=C2)C(=O)OCC
ethyl 2-bromobenzo[d]thiazole-6-carboxylate; CAS No.: 99073-88-8; ethyl 2-bromobenzo[d]thiazole-6-carboxylate. PROPERTIES: This compound presents a ethyl 2-bromobenzo[d]thiazole-6-carboxylate structure, combining an ethyl ester, a bromine atom, and a benzo[d]thiazole ring system. It typically appears as a colorless to pale yellow crystalline solid with a molecular weight of approximately 290.1 g/mol (C11H9BrNO2S). The melting point ranges between 85-90 C, and it exhibits moderate solubility in organic solvents such as ethyl acetate, dichloromethane, and tetrahydrofuran while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety precautions include wearing gloves, eye protection, and a lab coat. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: Ethyl 2-bromobenzo[d]thiazole-6-carboxylate is utilized in organic synthesis as a versatile intermediate. Its ethyl 2-bromobenzo[d]thiazole-6-carboxylate structure enables participation in various reactions, including nucleophilic substitution at the bromine atom and ester hydrolysis. In pharmaceutical research, it serves as a building block for synthesizing bioactive molecules, particularly those targeting the central nervous system and cancer. The bromine atom can be displaced to introduce amine or alcohol groups, while the ester can be hydrolyzed to a carboxylic acid for further functionalization. This compound also functions as a key intermediate in the synthesis of agrochemicals (though agricultural applications are excluded here). Academic studies employ it as a model compound in Organic Chemistry journals, focusing on the development of novel synthetic routes and reactivities of ethyl 2-bromobenzo[d]thiazole-6-carboxylate derivatives.
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