ethyl 2-(3-oxocyclopentyl)acetate
$400.00
CAS No.: 62457-60-7
Catalog No.: 192061
Purity: 95%
MF: C9H14O3
MW: 170.208
Storage: 2-8 degree Celsius
SMILES: O=C1CC(CC1)CC(=O)OCC
Catalog No.: 192061
Purity: 95%
MF: C9H14O3
MW: 170.208
Storage: 2-8 degree Celsius
SMILES: O=C1CC(CC1)CC(=O)OCC
ethyl 2-(3-oxocyclopentyl)acetate; CAS No.: 62457-60-7; ethyl 2-(3-oxocyclopentyl)acetate. PROPERTIES: Ethyl 2-(3-oxocyclopentyl)acetate is a colorless to pale yellow liquid with molecular formula C9H14O3. It has a molar mass of 170.20 g/mol and exhibits good solubility in common organic solvents like ethyl acetate and methanol but limited water solubility. The compound has a boiling point around 185-190 C at atmospheric pressure. Storage should be in tightly sealed containers in a cool, dry place (below 20 C) away from direct sunlight. Safety precautions include using chemical-resistant gloves and safety goggles. The compound may cause eye irritation, so immediate rinsing with water is required upon contact. If inhaled, moving to fresh air and providing oxygen if needed is advised. The material should be stored away from heat and open flames as it is combustible. APPLICATIONS: In pharmaceutical development, ethyl 2-(3-oxocyclopentyl)acetate serves as a versatile intermediate for creating non-steroidal anti-inflammatory agents. Medicinal chemistry groups have used this compound to synthesize cyclooxygenase inhibitors with improved selectivity profiles. The cyclopentyl ketone group provides a framework for developing COX-2 selective inhibitors. In medicinal chemistry, the compound has been explored as a lead for creating beta-blockers. A study published in a medicinal chemistry journal demonstrated how derivatives of ethyl 2-(3-oxocyclopentyl)acetate exhibited cardioselective beta-adrenergic blocking activity. Additionally, in materials science, the compound's ester group makes it suitable for use in polymer chemistry. Researchers at a polymer science laboratory incorporated ethyl 2-(3-oxocyclopentyl)acetate into polyurethane formulations to enhance the flexibility and durability of coatings.
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