![benzyl 4-(5-((64S,4S,Z)-4-((tert-butoxycarbonyl)amino)-11-ethyl-10,10-dimethyl-5,7-dioxo-11H-8-oxa-62,63-diaza-2(4,2)-thiazola-1(5,3)-indola-6(2,4)-bicyclo[3.1.1]heptanacycloundecaphane-12-yl)-6-((S)-1-methoxyethyl)pyridin-3-yl)piperazine-1-carboxylate](https://www.chemshuttle.com/media/catalog/product/cache/31dbf0bffbfa69a5826a72cec9a446de/2/0/200359_4.jpg)
Pan-RAS-IN-2(ERAS-0015, JPR0015)
$550.00
CAS No.: 3034673-92-9
Catalog No.: 200348
Purity: 95%
MF: C46H60N8O5S
MW: 837.08
Storage: 2-8 degree Celsius
SMILES: O=C1OCC(C)(CC2=[C@@]([C@@]3=C([C@@H](C)OC)N=CC(N4CCN(CC4)C)=C3)N(CC)C5=CC=C(C6=CSC(C[C@H](C(N7N[C@H]1C8CC7C8)=O)NC([C@H]9[C@@H]([C@@H]9C)C)=O)=N6)C=C25)C
Catalog No.: 200348
Purity: 95%
MF: C46H60N8O5S
MW: 837.08
Storage: 2-8 degree Celsius
SMILES: O=C1OCC(C)(CC2=[C@@]([C@@]3=C([C@@H](C)OC)N=CC(N4CCN(CC4)C)=C3)N(CC)C5=CC=C(C6=CSC(C[C@H](C(N7N[C@H]1C8CC7C8)=O)NC([C@H]9[C@@H]([C@@H]9C)C)=O)=N6)C=C25)C
For R&D use only. Not for human or veterinary use.
ERAS-0015 (JYP0015) is a tricomplex inhibitor that targets active RAS. It binds to cyclophilin A (CYPA) to form a high-affinity complex, which sterically blocks the interaction between RAS and its effectors. It shows potential in the study of RAS-mutant solid tumors.
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