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RM-018 CAS No.: 2641993-55-5 is a potent, functionally distinct tricomplex KRAS G12C active-state inhibitor. RM-018 retains the ability to bind and inhibit KRAS G12C/Y96D and could overcome resistance. RM-018 binds specifically to the GTP-bound, active [ RAS(ON) ] state of KRAS G12C.
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