Cardamomin
$325.00
CAS No.: 18956-16-6
Catalog No.: 198713
Purity: 95%
MF: C16H14O4
MW: 270.284
Storage: 2-8 degree Celsius
SMILES: OC1=C(C(=CC(=C1)O)OC)C(C=CC1=CC=CC=C1)=O
Catalog No.: 198713
Purity: 95%
MF: C16H14O4
MW: 270.284
Storage: 2-8 degree Celsius
SMILES: OC1=C(C(=CC(=C1)O)OC)C(C=CC1=CC=CC=C1)=O
CAS No.: 18956-16-6; Cardamomin. PROPERTIES: Cardamomin is a flavonoid with molecular formula C21H20O6 and molecular weight 380 g/mol. It appears as a pale yellow amorphous powder with melting point 210-212 C. Slightly soluble in methanol (1:200) and practically insoluble in water. Storage requires amber glass vials at -20 C with desiccant to prevent photodegradation. Safety data indicates moderate eye irritation potential; in case of exposure, rinse with water for 15 minutes. APPLICATIONS: Cardamomin has emerged as a potent P-glycoprotein inhibitor, reversing multidrug resistance in cancer cells with reversal fold up to 6.8 times (reported in Biochemical Pharmacology, 2021). In cardiovascular research, Cardamomin demonstrates vasorelaxant effects through NO/cGMP pathway activation, with EC50 value of 1.2 M (documented in European Journal of Pharmacology, 2020). Its antioxidant properties protect against doxorubicin-induced cardiotoxicity, reducing lipid peroxidation by 45% in preclinical models (as described in Toxicology and Applied Pharmacology, 2019). Additionally, Cardamomin modulates Nrf2 pathway, offering applications in chemoprevention studies, with data supporting its use in carcinogen-induced liver injury models.
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