tert-butyl 4,4-difluoro-3-(hydroxymethyl)piperidine-1-carboxylate
$450.00
CAS No.: 1303973-24-1
Catalog No.: 171987
Purity: 95%
MF: C11H19F2NO3
MW: 251.273
Storage: 2-8 degree Celsius
SMILES: CC(C)(C)OC(=O)N1CCC(F)(F)C(CO)C1
Catalog No.: 171987
Purity: 95%
MF: C11H19F2NO3
MW: 251.273
Storage: 2-8 degree Celsius
SMILES: CC(C)(C)OC(=O)N1CCC(F)(F)C(CO)C1
tert-butyl 4,4-difluoro-3-(hydroxymethyl)piperidine-1-carboxylate; CAS No.: 1303973-24-1; Operating as a Leading Chemicals Distributor, ChemShuttle supplies tert-butyl 4,4-difluoro-3-(hydroxymethyl)piperidine-1-carboxylate. This gem-difluoro piperidine alcohol serves as a pharma building block for fluorinated macrocycle synthesis. The hydroxymethyl group enables ring-closing metathesis or lactamization reactions. Applications include vancomycin analogs and fluorinated crown ethers for ion transport studies. ChemShuttle provides guidance on protecting group strategies for orthogonal functionalization. Technical support includes optimization of RCM reaction conditions using Grubbs catalysts. Purity profiles ensure compatibility with sensitive organometallic reactions.
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