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(S)-(2-amino-1-phenyl-ethyl)-carbamic acid benzyl ester; CAS No.: 130406-36-9; (S)-(2-amino-1-phenyl-ethyl)-carbamic acid benzyl ester. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C15H16N2O2 and a molecular weight of 252.30 g/mol. It exhibits a melting point in the range of 98-102 C and demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as (S)-(2-amino-1-phenyl-ethyl)-carbamic acid benzyl ester may cause skin irritation. The carbamate group requires careful handling in strongly acidic environments. APPLICATIONS: In medicinal chemistry, (S)-(2-amino-1-phenyl-ethyl)-carbamic acid benzyl ester serves as a key intermediate for synthesizing antidepressant agents, as documented in pharmaceutical research focusing on serotonergic compounds. Its amino group enables formation of bioactive amides through amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with insecticidal activities through formation of urea derivatives. Academic studies have explored its potential in bioconjugation reactions for creating targeted therapeutic agents, as reported in biochemical journals. The carbamate-protected amine group also facilitates controlled deprotection strategies in multi-step organic syntheses, as evidenced by methodological publications in synthetic chemistry.