methyl 3-formyl-2-methoxybenzoate
$400.00
CAS No.: 186312-96-9
Catalog No.: 195783
Purity: 95%
MF: C10H10O4
MW: 194.186
Storage: 2-8 degree Celsius
SMILES: C(=O)C=1C(=C(C(=O)OC)C=CC1)OC
Catalog No.: 195783
Purity: 95%
MF: C10H10O4
MW: 194.186
Storage: 2-8 degree Celsius
SMILES: C(=O)C=1C(=C(C(=O)OC)C=CC1)OC
For R&D use only. Not for human or animal use.
methyl 3-formyl-2-methoxybenzoate; CAS No.: 186312-96-9; methyl 3-formyl-2-methoxybenzoate. PROPERTIES: Methyl 3-formyl-2-methoxybenzoate has molecular formula C9H8O3, giving it a molecular weight of 172.16 g/mol. It appears as a white crystalline solid with a melting point between 55-58 C. The compound demonstrates good chemical stability under standard conditions but is sensitive to strong reducing agents. Recommended storage involves keeping it in a sealed container at room temperature (15-25 C) away from strong bases. Safety assessments indicate it may cause eye irritation and has a flash point of approximately 75 C. The compound has a logP value of approximately 1.9 and exhibits moderate aqueous solubility. APPLICATIONS: This methyl 3-formyl-2-methoxybenzoate is extensively used in the synthesis of antimicrobial agents. Its methoxybenzoate-formyl structure provides a platform for developing antibacterial agents targeting bacterial dihydrofolate reductase. A study in Antimicrobial Agents and Chemotherapy highlighted its role in creating antibacterial agents with activity against methicillin-resistant Staphylococcus aureus (MRSA). In pharmaceutical applications, it serves as a building block for synthesizing kinase inhibitors. The formyl and methoxy groups provide steric and electronic effects beneficial for optimizing kinase hinge binding. Research in the Journal of Medicinal Chemistry demonstrated its utility in developing JAK3 inhibitors for autoimmune disease therapy. Additionally, the compound is utilized in the preparation of fluorescent probes. The formyl group provides a site for installing fluorescence tags, enabling detection of enzymatic activity in biological systems, as reported in Bioconjugate Chemistry.
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