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3-methyl-6-nitro-[1,2,4]triazolo[4,3-a]pyridine
$180.00
CAS No.: 1715119-46-2
Catalog No.: LT0008
Purity: 95%
MF: C7H6N4O2
MW: 178.151
Storage: 2-8 degree Celsius
SMILES: CC1=NN=C2N1C=C(C=C2)[N+](=O)[O-]
Catalog No.: LT0008
Purity: 95%
MF: C7H6N4O2
MW: 178.151
Storage: 2-8 degree Celsius
SMILES: CC1=NN=C2N1C=C(C=C2)[N+](=O)[O-]
CAS NO.: 1715119-46-2;3-methyl-6-nitro-[1,2,4]triazolo[4,3-a]pyridine. PROPERTIES: This nitro-containing heterocycle presents as a pale yellow solid with a molecular weight of approximately 193.1 g/mol. The 3-methyl-6-nitro-[1,2,4]triazolo[4,3-a]pyridine combines a triazolopyridine framework with methyl and nitro substituents. It exhibits limited aqueous solubility but good dissolution in polar aprotic solvents like THF and CHCl3. Stability characterization reveals sensitivity to reducing agents and light exposure, necessitating storage at 2-8 degree Celsius in amber glass containers. Handlers should use powder hoods with HEPA filtration and wear cut-resistant gloves during handling. Skin contact may cause mild irritation requiring thorough washing. Inhalation may induce respiratory tract irritation; treatment includes fresh air and medical evaluation. Eye exposure requires extended rinsing and possible corticosteroid application. Waste should be hydrolyzed with dilute acid prior to disposal. APPLICATIONS: The 3-methyl-6-nitro-[1,2,4]triazolo[4,3-a]pyridine functions as a key intermediate in the synthesis of various pharmaceuticals. Its triazolopyridine framework provides privileged structure characteristics for receptor tyrosine kinase targeting. Research teams utilize this compound as a starting material for creating kinase inhibitors and ion channel modulators. The nitro group undergoes reduction to form amines for further functionalization. Additionally, it serves as a building block for creating fluorescent probes and bioimaging agents.
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