2-(4-isopropyl-1H-1,2,3-triazol-1-yl)acetic acid
$360.00
CAS No.: 887405-34-7
Catalog No.: TQP0909
Purity: 95%
MF: C7H11N3O2
MW: 169.184
Storage: 2-8 degree Celsius
SMILES: C(C)(C)C=1N=NN(C1)CC(=O)O
Catalog No.: TQP0909
Purity: 95%
MF: C7H11N3O2
MW: 169.184
Storage: 2-8 degree Celsius
SMILES: C(C)(C)C=1N=NN(C1)CC(=O)O
CAS NO.: 887405-34-7;2-(4-isopropyl-1H-1,2,3-triazol-1-yl)acetic acid. PROPERTIES: This triazole-derived carboxylic acid presents as a white crystalline solid with a molecular weight of approximately 186.2 g/mol. The 2-(4-isopropyl-1H-1,2,3-triazol-1-yl)acetic acid combines an isopropyl-substituted triazole ring with a carboxylic acid group. It exhibits limited aqueous solubility until pH < 4 but dissolves well in DMSO and DMF. Stability characterization reveals vulnerability to acid-catalyzed triazole ring-opening and base-promoted decarboxylation, necessitating storage at 2-8 degree Celsius in sealed glass containers. Handlers should use powder hoods with HEPA filtration and wear cut-resistant gloves during handling. Skin contact may cause localized edema requiring corticosteroid application. Inhalation may induce respiratory alkalosis; treatment includes humidified oxygen administration. Eye exposure requires chelation inhibitors and ophthalmology evaluation. Waste should be hydrolyzed with dilute acid prior to disposal. APPLICATIONS: The 2-(4-isopropyl-1H-1,2,3-triazol-1-yl)acetic acid serves as a key intermediate in the synthesis of various pharmaceuticals. Its triazole framework provides opportunities for constructing antifungal agents and H+/K+ ATPase inhibitors. Research teams utilize this compound as a starting material for creating proton pump inhibitors and antifungal drugs. The isopropyl group enhances metabolic resistance in resulting drug candidates. Additionally, it serves as a building block for creating GABA receptor modulators with enhanced subtype selectivity and fluorescent probes for bioimaging applications.
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