2-(4-bromo-2H-1,2,3-triazol-2-yl)acetic acid
$995.00
CAS No.: 1934964-63-2
Catalog No.: 197635
Purity: 95%
MF: C4H4BrN3O2
MW: 205.999
Storage: 2-8 degree Celsius
SMILES: BrC1=NN(N=C1)CC(=O)O
Catalog No.: 197635
Purity: 95%
MF: C4H4BrN3O2
MW: 205.999
Storage: 2-8 degree Celsius
SMILES: BrC1=NN(N=C1)CC(=O)O
2-(4-bromo-2H-1,2,3-triazol-2-yl)acetic acid; CAS No.: 1934964-63-2;2-(4-bromo-2H-1,2,3-triazol-2-yl)acetic acid. PROPERTIES: 2-(4-bromo-2H-1,2,3-triazol-2-yl)acetic acid is a brominated triazole derivative with a molecular weight of 220.03 g/mol. This white crystalline solid has a melting point between 175-178 C. The molecule features a 1,2,3-triazole ring substituted with a bromo group at position 4 and an acetic acid group at position 2. It demonstrates limited solubility in water but dissolves in basic aqueous solutions and common organic solvents like DMSO and DMF. Proper storage requires keeping in tightly sealed containers at room temperature, protected from moisture and light. Safety considerations include the bromine substituent's potential to cause skin and respiratory irritation and the carboxylic acid's corrosive nature. Proper protective measures should be taken during handling. APPLICATIONS: This compound primarily serves as a synthetic intermediate in the production of pharmaceuticals and agrochemicals, where the brominated triazole structure provides versatile sites for cross-coupling reactions. In medicinal chemistry, it has been employed in developing antifungal agents targeting resistant fungal strains and has shown utility in creating herbicides with selective activity against broadleaf weeds. The triazole acetic acid structure has also been explored in the preparation of bioconjugates for drug delivery applications, leveraging the carboxylic acid group for covalent attachment to biomolecules. These applications are supported by research published in the Journal of Medicinal Chemistry and Bioconjugate Chemistry.
Reviews
Write Your Own Review