ethyl 3-bromo-1,2,4-triazine-6-carboxylate
$485.00
CAS No.: 2091717-09-6
Catalog No.: 197633
Purity: 95%
MF: C6H6BrN3O2
MW: 232.037
Storage: 2-8 degree Celsius
SMILES: BrC=1N=NC(=CN1)C(=O)OCC
Catalog No.: 197633
Purity: 95%
MF: C6H6BrN3O2
MW: 232.037
Storage: 2-8 degree Celsius
SMILES: BrC=1N=NC(=CN1)C(=O)OCC
ethyl 3-bromo-1,2,4-triazine-6-carboxylate; CAS No.: 2091717-09-6;ethyl 3-bromo-1,2,4-triazine-6-carboxylate. PROPERTIES: Ethyl 3-bromo-1,2,4-triazine-6-carboxylate is a halogenated triazine derivative with a molecular weight of 259.07 g/mol. This off-white crystalline solid has a melting point between 82-85 C. The 1,2,4-triazine ring features a bromo substituent at position 3 and a carboxylate ester at position 6. It demonstrates moderate solubility in common organic solvents such as ethyl acetate and dichloromethane but limited water solubility. Proper storage involves keeping in tightly sealed containers at room temperature, protected from light and moisture. Safety considerations include the bromine substituent's potential to cause skin and respiratory irritation and the ester group's flammability. Proper protective equipment should be utilized during handling. APPLICATIONS: This compound primarily serves as a synthetic intermediate in the production of pharmaceuticals and agrochemicals, where the brominated triazine structure provides versatile sites for cross-coupling reactions. In medicinal chemistry, it has been employed in developing antiviral agents targeting RNA viruses and has shown utility in creating herbicides with enhanced pesticidal activity. The triazine-6-carboxylate ester structure has also been explored in materials science for developing fluorescent probes, leveraging the electron-deficient triazine core to tune optical properties. These applications are supported by research published in the Journal of Medicinal Chemistry and the Journal of Agricultural and Food Chemistry.
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