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methyl thiane-4-carboxylate; CAS No.: 128094-82-6; Methyl thiane-4-carboxylate provides a sulfur-containing six-membered ring for prodrug design. The ester group enables hydrolysis to carboxylic acid in vivo. Our library of compounds includes such saturated thioethers to improve metabolic stability compared to aromatic analogs in cardiovascular drug candidates.