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2-methyl-7,8-dihydro-3H-thiopyrano[4,3-d]pyrimidin-4(5H)-one; CAS No.: 284028-90-6; 2-methyl-7,8-dihydro-3H-thiopyrano[4,3-d]pyrimidin-4(5H)-one. PROPERTIES: This compound is a 2-methyl-7,8-dihydro-3H-thiopyrano[4,3-d]pyrimidin-4(5H)-one appearing as white crystalline powder. Its molecular weight is approximately 215.25 g/mol. It has melting point around 130-135 C. The compound is moderately soluble in polar organic solvents like dimethylformamide and dimethyl sulfoxide. It's moisture sensitive and may oxidize upon exposure to air. Store in tightly sealed containers under nitrogen atmosphere. Keep below 25 C and protect from moisture and light. Handle with care using appropriate protective equipment when handling powder. APPLICATIONS: 2-methyl-7,8-dihydro-3H-thiopyrano[4,3-d]pyrimidin-4(5H)-one is utilized in organic synthesis as thiopyrano[4,3-d]pyrimidine building block as detailed in Synthetic Communications. It's employed in preparation of certain antiviral compounds mentioned in Antiviral Research. Additionally, this compound serves as intermediate for synthesizing thiopyranopyrimidine-containing pharmaceuticals reported in Journal of Medicinal Chemistry. The methyl group provides valuable steric effects beneficial in drug design applications.