tert-butyl 5-bromothiophen-3-ylcarbamate
$300.00
CAS No.: 494833-75-9
Catalog No.: 196094
Purity: 95%
MF: C9H12BrNO2S
MW: 278.171
Storage: 2-8 degree Celsius
SMILES: BrC1=CC(=CS1)NC(OC(C)(C)C)=O
Catalog No.: 196094
Purity: 95%
MF: C9H12BrNO2S
MW: 278.171
Storage: 2-8 degree Celsius
SMILES: BrC1=CC(=CS1)NC(OC(C)(C)C)=O
tert-butyl 5-bromothiophen-3-ylcarbamate; CAS No.: 494833-75-9; tert-butyl 5-bromothiophen-3-ylcarbamate. PROPERTIES: tert-butyl 5-bromothiophen-3-ylcarbamate is a crystalline solid with a molecular weight of approximately 275.1 g/mol. It has a melting point between 90-95 C. The compound is moderately soluble in common organic solvents like ethyl acetate and tetrahydrofuran but is practically insoluble in water. The tert-butyl group provides steric protection to the carbamate linkage. For proper storage, keep in a tightly sealed container at room temperature away from heat and moisture. Safety: This compound may cause skin irritation and serious eye damage. In case of contact with skin, wash immediately with plenty of water and remove contaminated clothing. Use personal protective equipment including safety glasses and laboratory coats. APPLICATIONS: In pharmaceutical research, tert-butyl 5-bromothiophen-3-ylcarbamate serves as a protected amino acid derivative. The Boc group protects the amine during synthetic manipulations. In organic synthesis, it is used as a building block for creating bioactive molecules. The bromine substituent allows for cross-coupling reactions to introduce therapeutic groups. In materials science, derivatives of this compound are explored for creating molecular sensors. The combination of the thiophene ring and the carbamate group creates a scaffold that can selectively bind certain metal ions. These applications are documented in medicinal chemistry journals and materials science research articles.
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