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CAS No.: 102121-01-7; N 0734 hydrochloride. PROPERTIES: N 0734 hydrochloride is a crystalline powder with a molecular weight of approximately 327.8 g/mol. Its chemical formula is C8H12ClN5O. The compound is highly soluble in water and ethanol. It should be stored at room temperature in tightly sealed containers. Stability studies indicate no significant degradation over two years when properly stored. Safety precautions include avoiding release to the environment and using PPE during handling. The substance is harmful if swallowed and may cause respiratory tract irritation. APPLICATIONS: N 0734 hydrochloride is a selective antagonist of the adenosine A3 receptor. It is utilized in pharmacological research to study the role of A3 receptors in inflammatory and immune responses. In vitro studies show its ability to modulate cytokine production in immune cells. The compound has been explored in models of inflammatory bowel disease and rheumatoid arthritis. Additionally, N 0734 hydrochloride serves as a research tool for investigating the therapeutic potential of A3 receptor antagonism in cancer therapy, particularly in tumors with high A3 receptor expression. These applications are supported by scientific publications from medicinal chemistry and pharmacology research groups.