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(E)-4-(thiophen-2-yl)but-3-en-2-one; CAS No.: 33603-63-3; ChemShuttle s (E)-4-(thiophen-2-yl)but-3-en-2-one is a chalcone analog for natural product-inspired drug discovery. The , -unsaturated ketone enables Michael addition reactions in flavonoid synthesis. The company s CRO services include stability testing under accelerated degradation conditions.