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5-(thiophen-2-yl)pentanoic acid; CAS No.: 21010-06-0; 5-(thiophen-2-yl)pentanoic acid. PROPERTIES: 5-(thiophen-2-yl)pentanoic acid is a crystalline solid. Its molecular formula is C9H12O2S, and the molecular weight is approximately 196.27 g/mol. The compound has a melting point of approximately 80-82 C. It is moderately soluble in common organic solvents such as methanol and ethyl acetate, but is poorly soluble in water. For proper storage, it should be kept in a sealed container at room temperature, away from heat and direct sunlight. As a compound containing a thiophene ring and a carboxylic acid group, it may exhibit certain reactivity and stability. When handling it, protective gloves and eye protection should be worn. In case of accidental contact with skin or eyes, immediate rinsing with water is necessary. APPLICATIONS: In organic synthesis, 5-(thiophen-2-yl)pentanoic acid serves as a versatile intermediate. The carboxylic acid group can undergo reactions such as esterification and amidation. The thiophene ring provides unique electronic effects. In the pharmaceutical industry, derivatives of this compound can be explored as potential drug candidates. For example, in the development of certain antimicrobial agents, the structure of 5-(thiophen-2-yl)pentanoic acid can be modified to enhance the drug's antimicrobial activity and selectivity (as reported in medicinal chemistry journals). Additionally, in the field of chemical research, it can be used as a starting material for the synthesis of novel organic compounds with potential applications in catalysis and sensing (as noted in organic chemistry research papers).