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5-(methoxycarbonyl)thiophene-2-carboxylic acid; CAS No.: 50340-79-9; This ester-acid hybrid (5-(methoxycarbonyl)thiophene-2-carboxylic acid) from ChemShuttle allows orthogonal derivatization strategies. The methyl ester protects one carboxyl group during selective amidation of the other. The company provides guidance on tandem hydrolysis-condensation reactions.