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3-methoxythiophene-2-carboxylic acid; CAS No.: 60166-83-8; 3-methoxythiophene-2-carboxylic acid. PROPERTIES: 3-methoxythiophene-2-carboxylic acid is a crystalline solid. Its molecular formula is C5H5O3S, and the molecular weight is approximately 153.16 g/mol. The compound has a melting point of approximately 100-102 C. It is slightly soluble in water but dissolves well in organic solvents such as methanol and ethyl acetate. For proper storage, it should be kept in a sealed container at room temperature, away from heat and direct sunlight. As a compound containing a thiophene ring, a methoxy group, and a carboxylic acid group, it may exhibit certain reactivity and stability. When handling it, protective gloves and eye protection should be worn. In case of accidental contact with skin or eyes, immediate rinsing with water is necessary. APPLICATIONS: In organic synthesis, 3-methoxythiophene-2-carboxylic acid serves as a versatile intermediate. The carboxylic acid group can undergo reactions such as esterification and amidation. The methoxy group can be converted to other functional groups such as hydroxyl or halide. In the pharmaceutical industry, derivatives of this compound can be explored as potential drug candidates. For example, in the development of certain antimicrobial agents, the structure of 3-methoxythiophene-2-carboxylic acid can be modified to enhance the drug's antimicrobial activity and selectivity (as described in medicinal chemistry research articles). Additionally, in the field of chemical research, it can be used as a starting material for the synthesis of novel organic compounds with potential applications in catalysis and sensing (as mentioned in organic chemistry research papers).