2-(trifluoromethyl)thiophenol
$200.00
CAS No.: 13333-97-6
Catalog No.: WLZ1585
Purity: 95%
MF: C7H5F3S
MW: 178.178
Storage: 2-8 degree Celsius
SMILES: FC(C1=C(C=CC=C1)S)(F)F
Catalog No.: WLZ1585
Purity: 95%
MF: C7H5F3S
MW: 178.178
Storage: 2-8 degree Celsius
SMILES: FC(C1=C(C=CC=C1)S)(F)F
CAS NO.: 13333-97-6; 2-(trifluoromethyl)thiophenol. PROPERTIES: This sulfur-containing aromatic compound features a trifluoromethyl group attached to a thiophenol ring, creating a molecule with potential applications in organic synthesis and pharmaceutical research. The 2-(trifluoromethyl)thiophenol typically appears as a colorless to pale yellow liquid with moderate solubility in common organic solvents. Its molecular structure includes a thiophenol group that can participate in sulfur-centric reactions and a trifluoromethyl substituent that influences the electronic properties of the aromatic system. For optimal stability and to prevent oxidation of the sulfur atom, this compound should be stored at 2-8 degree Celsius in an amber glass bottle under an inert atmosphere. When handling, appropriate safety measures including nitrile gloves and safety goggles are recommended. This compound is sensitive to light and oxygen, requiring careful environmental control during storage and use. In case of skin contact, wash thoroughly with soap and water; if eye contact occurs, rinse immediately and seek medical evaluation. APPLICATIONS: The 2-(trifluoromethyl)thiophenol serves as a versatile building block in organic synthesis, particularly for creating sulfur-containing bioactive molecules. The thiophenol group provides a handle for further reactions such as oxidation or alkylation. In medicinal chemistry, this compound functions as an intermediate for developing pharmaceuticals targeting enzyme inhibitors and receptor modulators. The trifluoromethyl group contributes to target binding affinity and selectivity. Additionally, the molecule finds utility in materials science as a precursor for creating conductive polymers and other advanced materials where sulfur-containing moieties impart specific electronic properties. Researchers utilizing this compound can benefit from its functional group versatility, enabling the development of diverse molecular architectures for applications ranging from drug discovery to advanced materials.
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