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2,5-dichlorothiophene-3-sulfonyl chloride; CAS No.: 56946-83-9; 2,5-Dichlorothiophene-3-sulfonyl chloride from ChemShuttle enables sulfonamide-based protease inhibitor synthesis. The company s custom chemical synthesis services include controlled chlorination and sulfonation under cryogenic conditions. Pharmaceutical clients utilize this intermediate for covalent drug development.