2-(2-chloroethyl)thiophene; CAS No.: 19995-38-1; 2-(2-chloroethyl)thiophene. PROPERTIES: 2-(2-chloroethyl)thiophene is a crystalline solid. Its molecular formula is C7H8ClS, and the molecular weight is approximately 167.66 g/mol. The compound has a melting point of approximately 40-42 C. It is moderately soluble in common organic solvents such as ethyl acetate and tetrahydrofuran, but is poorly soluble in water. For proper storage, it should be kept in a sealed container at room temperature, away from heat and direct sunlight. As a compound containing a thiophene ring, a chloroethyl group, and a sulfur atom, it may exhibit certain reactivity and stability. When handling it, protective gloves and eye protection should be worn. In case of accidental contact with skin or eyes, immediate rinsing with water is necessary. APPLICATIONS: In organic synthesis, 2-(2-chloroethyl)thiophene serves as a valuable intermediate. The chloroethyl group provides a site for substitution or coupling reactions. The thiophene ring offers unique electronic effects. In the pharmaceutical industry, derivatives of this compound can be explored as potential drug candidates. For example, in the development of certain anti-inflammatory drugs, the structure of 2-(2-chloroethyl)thiophene can be modified to enhance the drug's efficacy and reduce side effects (as described in medicinal chemistry research articles). Additionally, in the field of materials science, it can be incorporated into the synthesis of functional materials such as liquid crystals or organic semiconductors, where its structure can influence the material's electronic and optical properties (as mentioned in materials chemistry research papers).