![thiazolo[4,5-d]pyrimidin-2-amine](https://www.chemshuttle.com/media/catalog/product/cache/31dbf0bffbfa69a5826a72cec9a446de/z/b/zb1187_1.jpg)
methyl 5-oxo-5H-thiazolo[3,2-a]pyrimidine-7-carboxylate
$800.00
CAS No.: 890092-78-1
Catalog No.: 197626
Purity: 95%
MF: C8H6N2O3S
MW: 210.214
Storage: 2-8 degree Celsius
SMILES: O=C1C=C(N=C2N1C=CS2)C(=O)OC
Catalog No.: 197626
Purity: 95%
MF: C8H6N2O3S
MW: 210.214
Storage: 2-8 degree Celsius
SMILES: O=C1C=C(N=C2N1C=CS2)C(=O)OC
methyl 5-oxo-5H-thiazolo[3,2-a]pyrimidine-7-carboxylate; CAS No.: 890092-78-1;methyl 5-oxo-5H-thiazolo[3,2-a]pyrimidine-7-carboxylate. PROPERTIES: Methyl 5-oxo-5H-thiazolo[3,2-a]pyrimidine-7-carboxylate is a fused heterocyclic compound with a molecular weight of 257.22 g/mol. This off-white crystalline solid has a melting point between 210-213 C. The molecule features a thiazolo[3,2-a]pyrimidine ring system with an oxo group at position 5 and a carboxylate ester at position 7. It demonstrates limited solubility in common organic solvents such as dimethylformamide and DMSO but is practically insoluble in water. Proper storage involves keeping in tightly sealed containers at room temperature, protected from moisture and light. Safety considerations include the oxo group's moderate toxicity and the ester group's flammability. Proper protective equipment should be utilized during handling. APPLICATIONS: This compound primarily functions as a synthetic intermediate in the production of anticancer and antiviral agents, where the fused heterocycle provides structural rigidity and the ester group offers a handle for further functionalization. In pharmaceutical development, it has been employed in creating kinase inhibitors and has shown promise in developing nucleoside analogs for antiviral therapy. The thiazolopyrimidine scaffold has also been explored in materials science for developing fluorescent probes, leveraging the electron-deficient heterocycle to tune optical properties. These applications are documented in publications from the Journal of Medicinal Chemistry and Chemical Communications.
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