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5,7-dichlorothiazolo[4,5-d]pyrimidine; CAS No.: 1137278-39-7; 5,7-dichlorothiazolo[4,5-d]pyrimidine. PROPERTIES: 5,7-dichlorothiazolo[4,5-d]pyrimidine is a crystalline compound with molecular formula C6H3Cl2N3S. It has a melting point between 220-225 C and exhibits limited solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its explosive nature when exposed to heat. APPLICATIONS: This dichlorinated thiazolopyrimidine is employed in the development of antimicrobial agents. The thiazolopyrimidine structure provides critical interactions with bacterial targets as reported in pharmaceutical chemistry journals. In materials science, 5,7-dichlorothiazolo[4,5-d]pyrimidine derivatives have found use in creating self-assembled monolayers for surface modification. According to materials chemistry journals, the thiazolopyrimidine core promotes adsorption onto metal surfaces while the chlorine substituents impart chemical resistance.