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thiazolo[4,5-b]pyridine-6-carboxylic acid; CAS No.: 1448852-06-9; thiazolo[4,5-b]pyridine-6-carboxylic acid. PROPERTIES: Thiazolo[4,5-b]pyridine-6-carboxylic acid is a white crystalline powder with a characteristic acidic pH in aqueous solution. The compound demonstrates thermal stability up to 200 C and shows good solubility in basic aqueous solutions. It exhibits characteristic IR absorption for carboxylic acid groups. Recommended storage involves maintaining in tightly sealed containers at room temperature. Safety protocols recommend avoiding dust inhalation and providing local exhaust ventilation as per ACGIH threshold limit values for organic acids. APPLICATIONS: Thiazolo[4,5-b]pyridine-6-carboxylic acid functions as an intermediate in the synthesis of SGLT2 inhibitors documented in diabetes research publications. Its carboxylic acid functionality enables formation of bioactive esters and amides explored in medicinal chemistry. Additionally, the compound serves as a building block for agrochemicals though this application is excluded, instead noting its role in materials science as a monomer for conducting polymers reported in polymer chemistry literature.