tert-butyl (2-bromothiazol-4-yl)carbamate
$300.00
CAS No.: 1245647-95-3
Catalog No.: 196082
Purity: 95%
MF: C8H11BrN2O2S
MW: 279.159
Storage: 2-8 degree Celsius
SMILES: BrC=1SC=C(N1)NC(OC(C)(C)C)=O
Catalog No.: 196082
Purity: 95%
MF: C8H11BrN2O2S
MW: 279.159
Storage: 2-8 degree Celsius
SMILES: BrC=1SC=C(N1)NC(OC(C)(C)C)=O
tert-butyl (2-bromothiazol-4-yl)carbamate; CAS No.: 1245647-95-3; tert-butyl (2-bromothiazol-4-yl)carbamate. PROPERTIES: tert-butyl (2-bromothiazol-4-yl)carbamate is a crystalline solid with a molecular weight of approximately 281.1 g/mol. It has a melting point between 110-115 C. The compound is moderately soluble in common organic solvents like ethyl acetate and tetrahydrofuran but is practically insoluble in water. The tert-butyl group provides steric protection to the carbamate linkage. For proper storage, keep in a tightly sealed container at room temperature away from heat and moisture. Safety: This compound may cause skin irritation and serious eye damage. In case of contact with skin, wash immediately with plenty of water and remove contaminated clothing. Use personal protective equipment including safety glasses and laboratory coats. APPLICATIONS: In pharmaceutical research, tert-butyl (2-bromothiazol-4-yl)carbamate serves as a protected amino acid derivative. The Boc group protects the amine during synthetic manipulations, and the bromine substituent allows for cross-coupling reactions. In organic synthesis, it is used as a building block for creating bioactive molecules. The thiazole ring provides structural features that enhance binding to biological targets. In materials science, derivatives of this compound are explored for creating molecular sensors. The combination of the thiazole ring and the carbamate group creates a scaffold that can selectively bind certain metal ions. These applications are documented in medicinal chemistry journals and materials science research articles.
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