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ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate; CAS No.: 161797-99-5; ChemShuttle's key intermediates include methylthiazole carboxylates for COX-2 inhibitor synthesis. The 4-hydroxyphenyl group and ethyl ester enable selective prostaglandin inhibition. Our Hantzsch thiazole formation achieves >95% yield through microwave assistance. This product serves as a precursor for diarylheterocycle-based anti-inflammatory agents with reduced GI toxicity.