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2-(3,5-dichlorophenyl)thiazole-4-carboxylic acid
$400.00
CAS No.: 1178420-52-4
Catalog No.: 196053
Purity: 95%
MF: C10H5Cl2NO2S
MW: 274.128
Storage: 2-8 degree Celsius
SMILES: ClC=1C=C(C=C(C1)Cl)C=1SC=C(N1)C(=O)O
Catalog No.: 196053
Purity: 95%
MF: C10H5Cl2NO2S
MW: 274.128
Storage: 2-8 degree Celsius
SMILES: ClC=1C=C(C=C(C1)Cl)C=1SC=C(N1)C(=O)O
2-(3,5-dichlorophenyl)thiazole-4-carboxylic acid; CAS No.: 1178420-52-4; 2-(3,5-dichlorophenyl)thiazole-4-carboxylic acid. PROPERTIES: 2-(3,5-dichlorophenyl)thiazole-4-carboxylic acid presents as a white crystalline powder with molecular formula C10H5Cl2NOS, possessing a molar mass of approximately 266.1 g/mol. It demonstrates limited water solubility but good solubility in hot methanol and DMSO. Melting point observations typically fall between 200-204 C. Proper storage requires maintaining in tightly sealed containers at room temperature, protected from light and moisture. Safety precautions highlight potential to cause serious eye damage and skin irritation. Proper handling involves using protective eyewear and gloves, with accidental release requiring containment with inert materials. APPLICATIONS: This compound functions as a key intermediate in the synthesis of anticancer agents, particularly those targeting tubulin polymerization. Its dichlorophenyl substituent at position 2 and carboxylic acid at position 4 enable selective modification for constructing bioactive molecules. In medicinal chemistry research, it supports the development of antibacterial agents through controlled derivatization pathways. The compound also contributes to materials science applications in photostabilizer development for polymer systems, with methodologies described in chemical literature and patent databases, demonstrating its cross-disciplinary utility in oncology and materials protection innovations.
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