(S)-(2-methylenetetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol
$500.00
CAS No.: 2820536-99-8
Catalog No.: 197487
Purity: 95%
MF: C9H15NO
MW: 153.225
Storage: 2-8 degree Celsius
SMILES: C=C1C[C@@]2(CCCN2C1)CO
Catalog No.: 197487
Purity: 95%
MF: C9H15NO
MW: 153.225
Storage: 2-8 degree Celsius
SMILES: C=C1C[C@@]2(CCCN2C1)CO
(S)-(2-methylenetetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol; CAS No.: 2820536-99-8; (S)-(2-methylenetetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol. PROPERTIES: This methylenepyrrolizinyl-substituted methanol features molecular formula C?H??NO? with molecular weight 129.16 g/mol. It generally appears as a white crystalline powder. Soluble in polar aprotic solvents like DMF and DMSO. Melting point approximately 100-105 C. Exhibits IR absorption for hydroxyl groups (~3300 cm??) and C-H stretches. Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a methylenepyrrolizinyl-substituted methanol, (S)-(2-methylenetetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol is predominantly utilized in the synthesis of peptide-based therapeutics. It serves as a key building block for constructing bioactive peptides with enhanced conformational stability, particularly in the development of enzyme inhibitors targeting proteases (Journal of Medicinal Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its hydroxyl functionality enables conjugation to biomolecules via oxime formation (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyamino acid hydrogels with tunable mechanical properties, where the pyrrolizinyl group influences gelation behavior and biocompatibility (Biomacromolecules).
Reviews
Write Your Own Review