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2-chloro-6-nitroquinoxaline; CAS No.: 6272-25-9; 2-chloro-6-nitroquinoxaline. PROPERTIES: 2-chloro-6-nitroquinoxaline is a crystalline compound with molecular formula C8H4ClN3O2, having a molar mass of approximately 213.6 g/mol. It demonstrates low water solubility but good solubility in dimethylformamide and DMSO. Melting point determinations typically yield values between 185-189 C. Proper storage requires maintaining in well-sealed containers at temperatures below 25 C, protected from light and moisture. Safety considerations identify it as harmful if swallowed and causing skin irritation. Precautionary measures recommend using explosion-proof ventilation and providing eyewash stations in handling areas. APPLICATIONS: This compound serves as a valuable intermediate in the synthesis of antiviral agents, particularly those targeting herpes simplex virus (HSV). Its chloro substituent at position 2 and nitro group at position 6 enable selective reduction and alkylation reactions crucial for constructing bioactive molecules. In agrochemical research (non-agricultural context), it contributes to safener compound development through controlled derivatization pathways. Additionally, the compound supports materials science applications in photodynamic therapy agents, with methodologies published in Antiviral Research and related pharmaceutical patents, illustrating its significance in antiviral therapy and materials science innovations.