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2-chloro-5-methoxyquinoxaline; CAS No.: 76052-76-1; 2-chloro-5-methoxyquinoxaline. PROPERTIES: 2-Chloro-5-methoxyquinoxaline presents as pale yellow crystals with a characteristic heterocyclic odor. The compound exhibits moderate polarity with a logP value approximately 2.1 and shows solubility in protic solvents like methanol. It is sensitive to strong nucleophiles and undergoes displacement reactions readily. Storage recommendations include amber glass containers and temperatures below 20 C. Safety precautions involve avoiding contact with strong reducing agents and using bonded containers to prevent static accumulation as per chemical handling guidelines. APPLICATIONS: 2-Chloro-5-methoxyquinoxaline serves as a key intermediate in the synthesis of quinolizidine alkaloids reported in total synthesis literature. Its chloro and methoxy substituents enable formation of diverse nitrogen-containing scaffolds useful in GABA receptor modulator research as documented in neuropharmacology journals. Furthermore, the compound contributes to synthesis of fluorescent probes for biomolecular imaging described in photochemistry communications.