7-(benzyloxy)-8-bromoquinoline
$275.00
CAS No.: 1647113-44-7
Catalog No.: 192521
Purity: 95%
MF: C16H12BrNO
MW: 314.182
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)OC1=CC=C2C=CC=NC2=C1Br
Catalog No.: 192521
Purity: 95%
MF: C16H12BrNO
MW: 314.182
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)OC1=CC=C2C=CC=NC2=C1Br
7-(benzyloxy)-8-bromoquinoline; CAS No.: 1647113-44-7; 7-(benzyloxy)-8-bromoquinoline. PROPERTIES: 7-(benzyloxy)-8-bromoquinoline is a crystalline powder with molecular formula C14H10BrNO. It has a melting point of approximately 90-95 C and exhibits moderate solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its flammable nature. APPLICATIONS: This benzyloxy, brominated quinoline is employed in the development of kinase inhibitors. The benzyloxy group provides unique binding affinity as described in cancer research literature. In medicinal chemistry, 7-(benzyloxy)-8-bromoquinoline serves as a key intermediate for creating central nervous system agents. According to pharmaceutical patents, the bromine substituent enhances blood-brain barrier penetration while the benzyloxy group offers metabolic stability.
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