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7-aminoquinoline-5-carboxylic acid; CAS No.: 1956341-10-8; 7-aminoquinoline-5-carboxylic acid. PROPERTIES: 7-aminoquinoline-5-carboxylic acid is a crystalline powder with a molecular weight of 213.2 g/mol. It has a melting point between 230 and 233 C (decomposition) and is moderately soluble in hot water and polar organic solvents. The compound is hygroscopic and should be stored in a sealed container with desiccant. It is sensitive to acidic conditions and may undergo hydrolysis in strongly basic environments. When handling, protective eyewear and gloves should be worn, and in case of eye contact, immediate rinsing with water is advised. APPLICATIONS: 7-aminoquinoline-5-carboxylic acid is utilized as a building block in the synthesis of pharmaceuticals, particularly in the development of antimalarial and anticancer agents. The amino group provides a site for further modification, while the carboxylic acid group allows for esterification or amide formation. In medicinal chemistry, 7-aminoquinoline-5-carboxylic acid is employed in the design of compounds targeting specific protein structures. It also serves as a precursor in the synthesis of quinoline-based dyes with applications in biological staining techniques. Additionally, the compound is used in the preparation of metal complexes for catalytic applications in organic transformations. These applications are typically encountered in pharmaceutical R&D laboratories and chemical manufacturing facilities specializing in heterocyclic compound production.